Shorting a biotech stock does not inherently limit your liability; in fact, it exposes you to potentially unlimited risks. When you short a stock, you borrow shares that you sell with the hope that the stock price will fall, allowing you to repurchase the shares at a lower price and return them to the lender while pocketing the difference. The challenge with this strategy is that while your potential gain is capped (the stock can only fall to zero), your potential loss is theoretically infinite since there is no ceiling on how high the stock price can rise.

A margin call does not limit your liability; instead, it is a mechanism by which your broker seeks to protect themselves from the risk of you defaulting on your borrowed position. If the price of the stock you are shorting rises beyond a certain point, your account may no longer meet the minimum equity requirements specified by the broker. In such a case, the broker will issue a margin call, requiring you to deposit additional funds or securities to cover the increased liability. Failing to meet a margin call can prompt the broker to liquidate your position, potentially at a loss.

Because biotech stocks can be particularly volatile due to factors like regulatory announcements, clinical trial results, and technological breakthroughs, shorting them involves significant risk. It’s essential to understand this risk, your broker’s margin requirements, and have a well-considered strategy in place before engaging in short selling, especially in sectors prone to rapid price fluctuations.

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